Myasthenia Gravis for a Nursing Program
Myasthenia gravis (MG) is a known autoimmune disease of the neuromuscular junction. It results in fluctuating muscle weakness and general fatigue or state of tiredness of the voluntary muscles (Joensen, 2014). This essay presents a review of two articles on Myasthenia Gravis, Myasthenia gravis incidence in a general North Atlantic isolated population by Joensen (2014) and Diurnal and day-to-day variation of isometric muscle strength in myasthenia gravis by Vinge, Jakobsen, Pedersen and Andersen (2016). The goal is to gain knowledge and improve understanding on myasthenia gravis.
MG is one of the autoimmune diseases. Both articles by Joensen (2014) and Vinge et al., (2016), state that MG is characterized by general fatigue of the voluntary muscles and fluctuating muscle weakness as a result of impaired neuromuscular transmission. Consequently, MG patients are projected to experience a gradual decrease of muscle strength throughout the day due to physical activities (Vinge et al., 2016). However, Vinge and colleagues (2016), through an isometric muscle strength analysis of the knee, shoulder, and ankle concluded that muscle strength decreases gradually both diurnally or day-to-day in both MG patients and controls. Besides, there are no significant differences in terms of decreasing muscle strength with physical activity in both MG patients and controls. Isometric muscle performance and variation of muscle strength does not depend in the time of the day (Vinge et al., 2016).It implies that variation in muscle weakness is not automatically greater among the MG patients compared with controls. Future research studies should aim to study and compare decreasing muscle strength given various demographic parameters such as sex, age, ethnicity, socioeconomic status, and race.
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